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What Does Zinc Have to Do With BPH, Cancer and Other Prostate Disease?
Did you know that more than 60% of American men are zinc deficient? Men’s sperm has zinc 100 times more than blood! Here’s another fact: You may have read somewhere that DHT (dihydrotestosterone) causes the prostate to grow.
STAND! Maybe I’m getting ahead of myself, let’s start again.
- The prostate gland is very unusual because it increases in size at various stages during most of a man’s life.
- The first stage of development is completed before or at birth, when the total prostate weighs about 1.5 grams.
- The second growth phase occurs early during puberty, when the weight of the prostate gland increases to around 11 grams.
- The third stage of growth occurs during the mid-20s, when the weight of the prostate gland increases to approximately 18 grams.
- wth phase that starts when a man is in his 50s. The amount varies depending on the men’s health.
- By the time a man is 70 years old, the prostate gland has reached a maximum size of 31 grams.
There is another clear Gro
Although the prostate gland grows during most of a man’s life, urinary problems Benign Prostatic Hypertrophy (BPH) and/or cancer often appear after the age of 50 as a result of the final growth stage.
Medical researchers don’t really know yet why the prostate gland enlarges during various developmental stages. However, there are two theories that try to explain this phenomenon. Both theories believe that hormonal changes over time are responsible.
(1) Changes in the normal balance of sex hormones. With advanced age, the amount of the male hormone testosterone The main male reproductive hormone. Conducted in experiments, it is responsible for the growth and development of the male reproductive organs and the development of characteristics such as a small voice, a unique distribution of male body hair, a relative lack of fat under the skin, and a large bone structure. , decreases in relation to the amount of circulating estrogen
A female hormone that is also normally present in small amounts in human blood, the primary female reproductive hormone that also circulates in men.
There is some evidence to suggest that this relative increase in circulating estrogen can strengthen the effect of the testosterone derivative DHT, which promotes cell growth in the prostate gland and is created when testosterone is acted upon by a specific enzyme. As a result of estrogen and DHT working together, cell growth and glandular enlargement are promoted.
NOTE: Ah-ha, DHT seems to be out of control and may be the cause of BPH. All wondering exactly what DHT is? Well here you go. DHT is a biologically active metabolite of the hormone testosterone, created primarily in the prostate gland, testicles, hair follicles, and adrenal glands by the enzyme 5a-reductase through a 4.5-fold reduction. DHT belongs to a class of compounds called androgens, also called androgenic hormones or testoids. Androgens are part of gender biology by directing and controlling the development and maintenance of male characteristics. DHT is 3 times more potent than testosterone; testosterone is 5-10 times more potent than adrenal androgens.
(2) Now here is the 2nd tip about DHT. Prostate gland development requires the conversion of testosterone into DHT. In the presence of a specific enzyme called 5-alpha reductase. As aging occurs, the amount of DHT in the prostate gland remains high, even as circulating testosterone levels drop.
Some evidence supports the idea that high levels of prostate DHT can itself promote cell growth and lead to enlargement.
Now after that introduction we come to zinc. The role of zinc in many cellular processes, including cell division (ah – that means it’s big – right?) and proliferation, immune function, and protection against free radicals, is well established. Zinc is the most abundant trace element in cells, and increasing evidence emphasizes zinc’s important role in both genetic stability and function.
Zinc deficiency can lead to immune dysfunction and impairments in growth, cognitive function, and hormone function. Over 2 billion people worldwide may be zinc deficient, you don’t need to be one of them.
Research has established a link between zinc deficiency and cancer is being established through human, animal, and cell culture studies. We also know that zinc status is compromised in cancer patients compared to healthy people.
Zinc also appears to play an important role in maintaining prostate health. Prostate cancer is the second leading cause of cancer death in American men, and many older men have some abnormal prostate cells. BPH may or may not be a precursor to prostate cancer. Human prostates normally accumulate the highest level of zinc of any tissue in the body, but we don’t know why. However, cancerous prostates have significantly less zinc than normal prostates, and many studies have implicated zinc deficiency in the development and progression of prostate cancer. There is also some evidence that increased dietary zinc is associated with a reduction in the incidence of prostate cancer.
Zinc supplements can not only help in the prevention of cancer, but can also play an important role in reducing its damage. As an antioxidant and component of many DNA repair proteins, zinc plays an important role in protecting DNA from damage. The current tolerable upper intake level for zinc is 40 mg/day, established by the US Academy of Medicine. Therefore, it is possible that the subjects in the epidemiologic study may have been exposed to toxic levels of zinc intake. As with most therapies, higher doses do not always equal an increase in
As a final note, zinc has some good side effects such as: effective in shortening cold symptoms, reducing the severity of cold sores, increasing energy levels, treating ADHD in children, fighting hair loss and controlling conditions such as hypoglycemia and diabetes. Negative effects of zine may include: Decreased copper, iron and magnesium levels, decrease your immune system function, and lower HDL (good cholesterol) level. Additional rare side effects may include: stomach upset, heartburn and nausea, fever, sore throat, mouth sores, weakness and fatigue.
There is some hope in clinical trials. Irving Bush, MD, professor of urology at the University of Health Sciences / Chicago Medical School, senior consultant at the center for the study of Genitourinary Diseases in West Dundee, Illinois, and former chairman of the Food and Drug Administration panel on gastroenterology, urology and Dialysis, conducted a small study of the use of zinc in the treatment of BPH. The men in the study took 150 milligrams of inc sulfate every day for two months, followed by 50 to 100 milligrams a day as a maintenance dose. Dr. Bush found that 14 of the 19 men experienced a shrinking of the prostate.
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